In Vivo (PK) Pharmacokinetics

The iterative nature of In Vivo Pharmacokinetic screening requires rapid cycle times with turn-on-a-dime changes in priorities. Agilux has built a team of experienced scientists with facilities and processes designed specifically to meet these challenging requirements. When combined with Agilux discovery bioanalysis, Agilux provides you with standard PK parameters from WinNonLin within 5 days of dosing.

Rapid In Vivo Pharmacokinetics Screening Studies

Agilux provides rapid In Vivo (PK) Pharmacokinetic  screening studies in rodent and non-rodent species. .Agilux is accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) and approved by the NIH Office of Laboratory Animal Welfare (OLAW).

From standard screening to more complex studies, our team of experienced Study Directors can also assist in designing the best strategy and protocols customized to suit any drug discovery program.

Rapid study initiations (within less than one week from initial request) and standardized abbreviated IACUC protocols with fully integrated LC-MS/MS bioanalysis of PK samples result in Better Data Faster.

The Agilux In Vivo PK screening service utilizes a wide variety of dose regimens and administration routes in both rodent and non-rodent species. We have standardized designs, but our experienced PI’s can also design, conduct, and interpret the In Vivo study to meet your specific requirements. Rapid study initiation is facilitated by our maintenance of a supply of rodents and a colony of non-rodent species.

The Agilux PK team has perfected techniques that allow evaluations on small volume samples, using conventional bioanalytical procedures. For example, we frequently perform the following small volume procedures:

• Serial sampling from mouse
• CSF sampling from mouse and rat

For more detailed information on our In Vivo services, please see the details below and contact us at info@agiluxlabs.com.